Marine toxins : origin, structure, and molecular pharmacology / Sherwood Hall and Gary Strichartz, editors.

Developed from a symposium held in Woods Hole, Massachusetts, under the auspices of the International Union of Pure and Applied Chemistry, and sponsored through an interagency agreement between the U.S. Army Medical Research Institute of Infectious Diseases and the Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration.

Symposium held on Aug. 27-30th, 1987.

Includes bibliographical references and index

Pharmacology of marine toxins : effects on membrane channels / Gary Strichartz and Neil Castle -- Biosynthesis of red tide toxins / Yuzuru Shimizu, Sandeep Gupta, and Hong-Nong Chou -- The saxitoxins : sources, chemistry, and pharmacology / Sherwood Hall, Gary Strichartz, E. Moczydlowski, A. Ravindran, and P.B. Reichardt -- High-performance liquid chromatographic method applied to paralytic shellfish poisoning research / John J. Sullivan -- A bacterial source of tetrodotoxins and saxitoxins / Mark L. Tamplin -- Natural toxins from cyanobacteria (blue-green algae) / Wayne W. Carmichael, Nik A. Mahmood, and Edward G. Hyde -- Nicotinic acetylcholine receptor function studied with synthetic (+)-anatoxin-a and derivatives / K.L. Swanson, H. Rapoport, R.S. Aronstam, and E.X. Albuquerque -- Polyether toxins involved in seafood poisoning / Takeshi Yasumoto and Michio Murata -- Ca-dependent excitatory effects of maitotoxin on smooth and cardiac muscle / Yasushi Ohizumi and Masaki Kobayashi -- X-ray crystallographic studies of marine toxins / Gregory D. Van Duyne -- Brevetoxins : unique activators of voltage-sensitive sodium channels / Vera L. Trainer, Richard A. Edwards, Alina M. Szmant, Adam M. Stuart, Thomas J. Mende, and Daniel G. Baden -- Detection, metabolism, and pathophysiology of brevetoxins / Mark A. Poli, Charles B. Templeton, Judith G. Pace, and Harry B. Hines -- The molecular basis of ciguatoxin action / Christian Frelin, Monique Durand-Clément, Jean-Noël Bidard, and Michel Lazdunski -- A perspective on palytoxin / Gary Strichartz -- Mechanism of palytoxin action on the epidermal growth factor receptor / Elizabeth V. Wattenberg, Hirota Fujiki, and Marsha Rich Rosner -- Mechanism of pharmacological action of palytoxin / Yasushi Ohizumi -- Production of antibodies and development of a radioimmunoassay for palytoxin / Lawrence Levine, Hirota Fujiki, Hilda B. Gjika, and Helen Van Vunakis -- New tumor promoters from marine natural products / Hirota Fujiki, Masami Suganuma, Hiroko Suguri, Shigeru Yoshizawa, Kanji Takagi, Michie Nakayasu, Makoto Ojika, Kiyoyuki Yamada, Takeshi Yasumoto, Richard E. Moore, and Takashi Sugimura -- Pharmacological and toxicological studies of palytoxin / James A. Vick and Joseph Wiles -- Conotoxins : targeted peptide ligands from snail venoms / Baldomero M. Olivera, David R. Hillyard, Jean Rivier, Scott Woodward, William R. Gray, Gloria Corpuz, and Lourdes J. Cruz -- Sea anemone polypeptide toxins affecting sodium channels : initial structure-activity investigations / William R. Kem, Michael W. Pennington, and Ben M. Dunn -- Solution structure of sea anemone toxins by NMR spectroscopy / N. Vasant Kumar, Joseph H.B. Pease, Hugues Schweitz, and David E. Wemmer -- Cytolytic peptides of sea anemones / Alan W. Bernheimer -- Toxins from marine invertebrates / M.J.A. Walker and V.L. Masuda -- Some natural jellyfish toxins / Joseph W. Burnett -- Neurotoxins from sea snake and other vertebrate venoms / Anthony T. Tu -- Origin, chemistry, and mechanisms of action of a repellent, presynaptic excitatory, ionophore polypeptide / P. Lazarovici, N. Primor, J. Gennaro, J. Fox, Y. Shai, P.I. Lelkes, C.G. Caratsch, G. Raghunathan, H.R. Guy, Y.L. Shih, and C. Edwards.

English eng